@article{Silva_Tavares_Correia_Freitas_santos_Carvalho_Malheiro_Cabrita_Rodrigues_2019, title={Exit site infection in peritoneal dialysis : predictive factors for adverse outcome}, volume={2}, url={https://bdd.rdplf.org/index.php/bdd/article/view/21333}, DOI={10.25796/bdd.v2i3.21333}, abstractNote={<p>Infection-related complications in patients on peritoneal dialysis (PD) is a leading complication.</p> <p>Our aim was to evaluate the type and natural course of ESI events in a cohort of PD treated in last decade of our PD program.</p> <p>Registry data of ESI events (n=126, in 74 patients<u>)</u> were retrieved. ESI protocols followed standard international guidelines. A systematic quality control is performed.</p> <p>               The median follow-up was 29.1 (14.0-47.4) months. In this population the adverse outcomes of TI rate and peritonitis rate was 0.12 and 0.13 patient/year, respectively.                Male sex (0.048), older age (0.007) and <em>Staphylococcus aureus</em> (SA) agent (0.006) were predictive of TI while non-optional PD and lower levels of albumin were predictive of peritonitis.                 After grouping the ESI events according to the date of the occurrence of infection (group 1: 2008 to 2012, group 2: 2013 to 2017 and group 3: 2018) a substantial increase of TI in 2018 was evident (P <0.001 when comparing group 3 vs 1 and 0.005 when comparing group 2 and 3).               When ESI occurs simultaneous with TI, the probability of not reaching cure is 65%. Drop-out occurred in 50% of ESI without peritonitis vs 86% with peritonitis (P <0.001). <em>SA</em> is the microorganism most implicated in the failure to heal (P 0.002) and drop-out (P 0.010).</p> <p>In spite of a number of efforts to reduce ESI, a regular audit still point to the need for protocols review in order to avoid adverse outcomes. Focused training of patients is mandatory but also prophylaxis and antibiotic protocols deserve improvement.</p>}, number={3}, journal={Bulletin de la Dialyse à Domicile}, author={Silva, Filipa Sofia and Tavares, Joana and Correia, Sofia O and Freitas, Cristina and santos, Olivia and Carvalho, Maria João and Malheiro, Jorge and Cabrita, António and Rodrigues, Anabela}, year={2019}, month={Sep.}, pages={127–134} }