Questioning one-size-fits-all dialysis prescription: balancing dialysis prescription and residual kidney function

Authors

DOI:

https://doi.org/10.25796/bdd.v6i1.74683

Keywords:

hemodialysis, incremental dialysis, residual renal function, home dialysis

Abstract

Recent awareness of the viability and benefits of incremental hemodialysis is an opportunity to review clinical practices and improve the process of dialysis induction. Incremental dialysis is a standard approach in peritoneal dialysis prescription, with a focus on the quality parameter of nephroprotection. The same should apply in hemodialysis, with individualization of the prescribed extracorporeal technique: frequency, duration and intensity, in either home or center hemodialysis, are prescription variables to adjust according to the patient’s residual renal function, medical condition and psycho-social priorities. Considering that fluid balance and smooth ultrafiltration critically impact patient survival, incremental dialysis schedules need to be carefully tailored and grounded in routine residual kidney function measurement. This paper raises concerns about both the benefits of incremental dialysis and its putative detrimental effects, these being mainly dependent on the quality of the hemodialysis prescription and external economic constraints. As a comparator, incremental peritoneal dialysis is a scientifically based model to pursue, whichever the modality, based on updated concepts of patient-centered prescription and adequacy in dialytic renal replacement therapies.

References

Scribner BH, Caner JE, Buri R, Quinton W. The technique of continous hemodialysis. Trans Am Soc Artif Intern Organs. 6:88–103.

Termorshuizen F, Dekker FW, van Manen JG, Korevaar JC, Boeschoten EW, Krediet RT, et al. Relative contribution of residual renal function and different measures of adequacy to survival in hemodialysis patients: an analysis of the Netherlands Cooperative Study on the Adequacy of Dialysis (NECOSAD)-2. J Am Soc Nephrol. 2004 Apr;15(4):1061–70.

Vilar E, Kaja Kamal RM, Fotheringham J, Busby A, Berdeprado J, Kislowska E, et al. A multicenter feasibility randomized controlled trial to assess the impact of incremental versus conventional initiation of hemodialysis on residual kidney function. Kidney Int. 2022 Mar;101(3):615–25.

Park JI, Park JT, Kim Y-L, Kang S-W, Yang CW, Kim N-H, et al. Comparison of outcomes between the incremental and thrice-weekly initiation of hemodialysis: a propensity-matched study of a prospective cohort in Korea. Nephrol Dial Transplant. 2016 Sep 28;gfw332.

Tangvoraphonkchai K, Davenport A. Incremental Hemodialysis – A European Perspective. Semin Dial. 2017;30(3):270–6.

Cheetham MS, Cho Y, Krishnasamy R, Jain AK, Boudville N, Johnson DW, et al. Incremental Versus Standard (Full-Dose) Peritoneal Dialysis. Kidney Int Reports. 2022;7(2):165–76.

Correia S, Silva F, Tavares J, Cabrita A, Queirós J. Online hemofiltration in incremental dialysis prescription. Port J Nephrol Hypertens. 2021;34(4):204–10.

Golper TA. Incremental dialysis: Review of recent literature. Curr Opin Nephrol Hypertens. 2017;26(6):543–7.

Perl J, Dember LM, Bargman JM, Browne T, Charytan DM, Flythe JE, et al. The Use of a Multidimensional Measure of Dialysis Adequacy—Moving beyond Small Solute Kinetics. Clin J Am Soc Nephrol. 2017 May;12(5):839–47.

Lima A, Tavares J, Pestana N, Carvalho MJ, Cabrita A, Rodrigues A. Sodium removal in peritoneal dialysis: is there room for a new parameter in dialysis adequacy? Bull la Dial à Domic. 2019 Sep 18;2(3):151–7.

Bernardo AP, Contesse SA, Bajo MA, Rodrigues A, Del Peso G, Ossorio M, et al. Peritoneal Membrane Phosphate Transport Status: A Cornerstone in Phosphate Handling in Peritoneal Dialysis. Clin J Am Soc Nephrol. 2011 Mar;6(3):591–7.

Bieber B, Qian J, Anand S, Yan Y, Chen N, Wang M, et al. Two-times weekly hemodialysis in China: Frequency, associated patient and treatment characteristics and quality of life in the China dialysis outcomes and practice patterns study. Nephrol Dial Transplant. 2014;29(9):1770–7.

Obi Y, Streja E, Rhee CM, Ravel V, Amin AN, Cupisti A, et al. Incremental Hemodialysis, Residual Kidney Function, and Mortality Risk in Incident Dialysis Patients: A Cohort Study. Am J Kidney Dis. 2016;68(2):256–65.

Rhee CM, Unruh M, Chen J, Kovesdy CP, Zager P, Kalantar-Zadeh K. Infrequent Dialysis: A New Paradigm for Hemodialysis Initiation. Semin Dial. 2013;26(6):720–7.

Hanson JA, Hulbert-Shearon TE, Ojo AO, Port FK, Wolfe RA, Agodoa LYC, et al. Prescription of twice-weekly hemodialysis in the USA. Am J Nephrol. 1999;19(6):625–33.

Chauhan R, Mendonca S. Adequacy of twice weekly hemodialysis in end stage renal disease patients at a tertiary care dialysis centre. Indian J Nephrol. 2015;25(6):329–33.

7 Adequacy of peritoneal dialysis. Nephrol Dial Transplant. 2005 Dec 1;20(suppl_9):ix24–7.

Brown EA, Blake PG, Boudville N, Davies S, de Arteaga J, Dong J, et al. International Society for Peritoneal Dialysis practice recommendations: Prescribing high-quality goal-directed peritoneal dialysis. Perit Dial Int J Int Soc Perit Dial. 2020 May 21;40(3):244–53.

Vanholder R, Annemans L, Bello AK, Bikbov B, Gallego D, Gansevoort RT, et al. Fighting the unbearable lightness of neglecting kidney health: the decade of the kidney. Clin Kidney J. 2021 Jun 24;14(7):1719–30.

Htay H, Johnson DW, Wiggins KJ, Badve S V, Craig JC, Strippoli GF, et al. Biocompatible dialysis fluids for peritoneal dialysis. Cochrane Database Syst Rev. 2018 Oct 26;2018(10).

Bricker NS, Morrin PAF KS. The pathologic physiology of chronic Bright’s disease: an exposition of the ‘intact nephron hypothesis’. Am J Med. 1960;28:77 – 98.

Golper TA, Mehrotra R. The intact nephron hypothesis in reverse: An argument to support incremental dialysis. Nephrol Dial Transplant. 2015;30(10):1602–4.

Herington JL, Crispens MA, Carvalho-macedo AC, Camargos AF, Lebovic DI, Bruner- KL, et al. Association of Residual Urine Output with Mortality, Quality of Life, and Inflammation in Incident Hemodialysis Patients: The CHOICE (Choices for Healthy Outcomes in Caring for End-Stage Renal Disease) Study. 2012;95(4):1295–301.

Lin YF, Huang JW, Wu MS, Chu TS, Lin SL, Chen YM, et al. Comparison of residual renal function in patients undergoing twice-weekly versus three-times-weekly haemodialysis. Nephrology. 2009;14(1):59–64.

Berlanga JR, Marrón B, Reyero A, Caramelo C, Ortiz A. Peritoneal dialysis retardation of progression of advanced renal failure. Perit Dial Int. 22(2):239–42.

Fernández-Lucas M, Teruel-Briones JL, Gomis-Couto A, Villacorta-Pérez J, Quereda-Rodríguez-Navarro C. Maintaining residual renal function in patients on haemodialysis: 5-year experience using a progressively increasing dialysis regimen. Nefrologia. 2012;32(6):767–76.

Zhang M, Wang M, Li H, Yu P, Yuan L, Hao C, et al. Association of initial twice-weekly hemodialysis treatment with preservation of residual kidney function in ESRD patients. Am J Nephrol. 2014;40(2):140–50.

Daugirdas JT, Greene T, Rocco M V., Kaysen GA, Depner TA, Levin NW, et al. Effect of frequent hemodialysis on residual kidney function. Kidney Int. 2013;83(5):949–58.

Moist LM, Port FK, Orzol SM, Young EW, Ostbye T, Wolfe RA, et al. Predictors of loss of residual renal function among new dialysis patients. J Am Soc Nephrol. 2000;11(3):556–64.

Jansen MAM, Hart AAM, Korevaar JC, Dekker FW, Boeschoten EW, Krediet RT, et al. Predictors of the rate of decline of residual renal function in incident dialysis patients. Kidney Int. 2002;62(3):1046–53.

Lang SM, Bergner A, Töpfer M SH. Preservation of residual renal function in dialysis patients: effects of dialysis-technique-related factors. Perit Dial Int. 2001;Jan-Feb.

McKane W, Chandna SM, Tattersall JE, Greenwood RN, Farrington K. Identical decline of residual renal function in high-flux biocompatible hemodialysis and CAPD. Kidney Int. 2002;61(1):256–65.

Lysaght MJ, Vonesh EF, Gotch F, Ibels L, Keen M, Lindholm B, et al. The influence of dialysis treatment modality on the decline of remaining renal function. ASAIO Trans. 37(4):598–604.

Teruel-Briones JL, Fernández-Lucas M, Rivera-Gorrin M, Ruiz-Roso G, Díaz-Domínguez M, Rodríguez-Mendiola N, et al. Progression of residual renal function with an increase in dialysis: haemodialysis versus peritoneal dialysis. Nefrologia. 2013;33(5):640–9.

Yeung EK, Brown L, Kairaitis L, Krishnasamy R, Light C, See E, et al. Impact of haemodialysis hours on outcomes in older patients. Nephrology. 2022 Nov 30;

Lee Y-J, Okuda Y, Sy J, Lee YK, Obi Y, Cho S, et al. Ultrafiltration Rate, Residual Kidney Function, and Survival Among Patients Treated With Reduced-Frequency Hemodialysis. Am J Kidney Dis. 2020 Mar;75(3):342–50.

Hwang HS, Hong YA, Yoon HE, Chang YK, Kim SY, Kim YO, et al. Comparison of Clinical Outcome Between Twice-Weekly and Thrice-Weekly Hemodialysis in Patients With Residual Kidney Function. Medicine (Baltimore). 2016 Feb;95(7):e2767.

Kong J, Davies M, Mount P. The importance of residual kidney function in haemodialysis patients. Nephrology. 2018 Dec;23(12):1073–80.

Caria S, Cupisti A, Sau G, Bolasco P. The incremental treatment of ESRD: a low-protein diet combined with weekly hemodialysis may be beneficial for selected patients. BMC Nephrol. 2014 Dec 29;15(1):172.

de Sequera P, Corchete E, Bohorquez L, Albalate M, Perez-Garcia R, Alique M, et al. Residual Renal Function in Hemodialysis and Inflammation. Ther Apher Dial. 2017 Dec;21(6):592–8.

Rroji M, Spahia N, Seferi S, Barbullushi M, Spasovski G. Influence of Residual Renal Function in Carotid Modeling as a Marker of Early Atherosclerosis in Dialysis Patients. Ther Apher Dial. 2017 Oct;21(5):451–8.

Chen H-C, Chou C-Y, Jheng J-S, Chen I-R, Liang C-C, Wang S-M, et al. Loss of Residual Renal Function is Associated With Vascular Calcification in Hemodialysis Patients. Ther Apher Dial. 2016 Feb;20(1):27–30.

Vilar E, Farrington K. Emerging Importance of Residual Renal Function in End-Stage Renal Failure. Semin Dial. 2011 Sep;24(5):487–94.

Asano M, Thumma J, Oguchi K, Pisoni RL, Akizawa T, Akiba T, et al. Vascular Access Care and Treatment Practices Associated with Outcomes of Arteriovenous Fistula: International Comparisons from the Dialysis Outcomes and Practice Patterns Study. Nephron Clin Pract. 2013 Sep 12;124(1–2):23–30.

In-Center Hemodialysis Six Times per Week versus Three Times per Week. N Engl J Med. 2010 Dec 9;363(24):2287–300.

Suri RS, Larive B, Sherer S, Eggers P, Gassman J, James SH, et al. Risk of Vascular Access Complications with Frequent Hemodialysis. J Am Soc Nephrol. 2013 Mar;24(3):498–505.

Soi V, Faber MD, Paul R. Incremental Hemodialysis: What We Know so Far. Int J Nephrol Renovasc Dis. 2022 Apr;Volume 15:161–72.

Mathew A, Obi Y, Rhee CM, Chen JLT, Shah G, Lau W-L, et al. Treatment frequency and mortality among incident hemodialysis patients in the United States comparing incremental with standard and more frequent dialysis. Kidney Int. 2016 Nov;90(5):1071–9.

Lin X, Yan Y, Ni Z, Gu L, Zhu M, Dai H, et al. Clinical Outcome of Twice-Weekly Hemodialysis Patients in Shanghai. Blood Purif. 2012;33(1–3):66–72.

Kalantar-Zadeh K, Crowley ST, Beddhu S, Chen JLT, Daugirdas JT, Goldfarb DS, et al. Renal Replacement Therapy and Incremental Hemodialysis for Veterans with Advanced Chronic Kidney Disease. Semin Dial. 2017 May;30(3):251–61.

Foley RN, Chen S-C, Solid CA, Gilbertson DT, Collins AJ. Early mortality in patients starting dialysis appears to go unregistered. Kidney Int. 2014 Aug;86(2):392–8.

Burton JO, Jefferies HJ, Selby NM, McIntyre CW. Hemodialysis-induced repetitive myocardial injury results in global and segmental reduction in systolic cardiac function. Clin J Am Soc Nephrol. 2009 Dec;4(12):1925–31.

Fagugli RM, Pasini P, Quintaliani G, Pasticci F, Ciao G, Cicconi B, et al. Association between extracellular water, left ventricular mass and hypertension in haemodialysis patients. Nephrol Dial Transplant. 2003 Nov;18(11):2332–8.

Gotch FA, Levin NW. Daily Dialysis: The Long and the Short of It. Blood Purif. 2003;21(4–5):271–81.

Daugirdas JT. Removal of Phosphorus by Hemodialysis. Semin Dial. 2015 Nov;28(6):620–3.

Paniagua R, Amato D, Vonesh E, Correa-Rotter R, Ramos A, Moran J, et al. Effects of Increased Peritoneal Clearances on Mortality Rates in Peritoneal Dialysis: ADEMEX, a Prospective, Randomized, Controlled Trial. J Am Soc Nephrol. 2002 May;13(5):1307–20.

Bargman JM, Thorpe KE, Churchill DN. Relative Contribution of Residual Renal Function and Peritoneal Clearance to Adequacy of Dialysis: A Reanalysis of the CANUSA Study. J Am Soc Nephrol. 2001 Oct;12(10):2158–62.

Murea M, Kalantar-Zadeh K. Incremental and Twice-Weekly Hemodialysis Program in Practice. Clin J Am Soc Nephrol. 2021 Jan 7;16(1):147–9.

Medcalf JF, Harris KPG, Walls J. Role of diuretics in the preservation of residual renal function in patients on continuous ambulatory peritoneal dialysis. Kidney Int. 2001 Mar;59(3):1128–33.

Davenport A. Measuring residual renal function in dialysis patients: can we dispense with 24-hour urine collections? Kidney Int. 2016 May;89(5):978–80.

Shafi T, Michels WM, Levey AS, Inker LA, Dekker FW, Krediet RT, et al. Estimating residual kidney function in dialysis patients without urine collection. Kidney Int. 2016 May;89(5):1099–110.

Bragg-Gresham JL, Fissell RB, Mason NA, Bailie GR, Gillespie BW, Wizemann V, et al. Diuretic Use, Residual Renal Function, and Mortality Among Hemodialysis Patients in the Dialysis Outcomes and Practice Pattern Study (DOPPS). Am J Kidney Dis. 2007 Mar;49(3):426–31.

Trinh E, Bargman JM. Are Diuretics Underutilized in Dialysis Patients? Semin Dial. 2016 Sep;29(5):338–41.

Li T, Wilcox CS, Lipkowitz MS, Gordon-Cappitelli J, Dragoi S. Rationale and Strategies for Preserving Residual Kidney Function in Dialysis Patients. Am J Nephrol. 2019;50(6):411–21.

Daugirdas JT, Depner TA, Inrig J, Mehrotra R, Rocco M V., Suri RS, et al. KDOQI Clinical Practice Guideline for Hemodialysis Adequacy: 2015 Update. Am J Kidney Dis. 2015 Nov;66(5):884–930.

Basile C, Casino FG, Aucella F. Incremental hemodialysis, a valuable option for the frail elderly patient. J Nephrol. 2019 Oct 19;32(5):741–50.

Published

2023-04-26

How to Cite

1.
Fernandes J, Soares Rodrigues A. Questioning one-size-fits-all dialysis prescription: balancing dialysis prescription and residual kidney function . Bull Dial Domic [Internet]. 2023 Apr. 26 [cited 2024 Dec. 22];6(1):13-24. Available from: https://bdd.rdplf.org/index.php/bdd/article/view/74683