Acceptance of vaccination against COVID-19 among peritoneal dialysis patients in Senegal

Authors

  • Hicham Ettoumi Centre hospitalier national Dalal Jamm
  • Mansour Mbengue Centre hospitalier national Dalal Jammp https://orcid.org/0000-0001-5720-8134
  • Abdou Niang Centre hospitalier national Dalal Jamm

DOI:

https://doi.org/10.25796/bdd.v6i2.76733

Keywords:

Covid-19, Peritoneal dialysis, Vaccination, Senegal

Abstract

Introduction
The aim of this study was to assess vaccination coverage among peritoneal dialysis patients and to identify factors associated with non-vaccination.
Patients and methods
This was a multicenter, retrospective, descriptive, and analytical study conducted over a 6-month period in 4 peritoneal dialysis units. Patients on peritoneal dialysis for at least 3 months were included.
Results
Forty-nine patients were included in our study. Of these, 30 (61.2%) were vaccinated against COVID-19, with a sex ratio of 0.8. Eighty-three percent of patients had received 2 doses. Of these, 63.3% had received the AstraZeneca vaccine, 33.3% Sinopharm, and 3.4% Johnson & Johnson. Adverse events were mainly pain at the inoculation site in 100% of cases and influenza-like illness in 25%. The reason for non-vaccination in 42% of cases was fear of vaccine side effects and/or minimization of the severity of COVID-19. Among vaccinated patients, 2 (6.6%) had tested positive for COVID-19 after vaccination, including one with a severe form 3 months after vaccination. The average age of vaccinated patients was significantly higher (47.6 years) than that of non-vaccinated patients (37.6 years) (p=0.048).
Conclusion
It is vital to continue applying COVID-19 prevention measures in the various peritoneal dialysis centers, and to encourage vaccination or completion of vaccination schedules, particularly in younger patients.

References

Chronologie de l’action de l’OMS face à la COVID-19 [Internet]. [Cité 20 juin 2022]. Disponible sur: https://www.who.int/fr/news/item/29-06-2020-covidtimeline.

COVID-19 Data Explorer [Internet]. Our World in Data. [Cité 20 juin 2022]. Disponible sur: https://ourworldindata.org/coronavirus-data-explorer

Le Sénégal déclare le premier cas de COVID-19 [Internet]. OMS | Bureau régional pour l’Afrique. [cité 20 juin 2022]. Disponible sur: https://www.afro.who.int/fr/news/le-senegal-declare-le-premier-cas-de-covid-19

Nouveau coronavirus (2019-nCov) : conseils au grand public – Quand et comment utiliser un masque ? [Internet]. [Cité 20 juin 2022]. Disponible sur: https://www.who.int/fr/emergencies/diseases/novel-coronavirus-2019/advice-for-public/when-and-how-to-use-masks .

Diagnosis and Treatment Protocol for Novel Coronavirus Pneumonia (Trial Version 7). Chin Med J (Engl). 2020;133(9):1087-95. doi: 10.1097/CM9.0000000000000819. - DOI - PMC - PubMed

Tsevi, Y.M., Djagadou, A.K., Kotosso, A., Bawe, L.D., Moukaïla, A.-R. and Djibril, A.M. (2022) The COVID-19 Vaccine Acceptance in Hemodialysis Patients in Togo. Open J Nephrol, 12, 162-168. https://doi.org/10.4236/ojneph.2022.121016

Bensouna I, Caudwell V, Kubab S, Acquaviva S, Pardon A, Vittoz N, Bozman DF, Hanafi L, Faucon AL, Housset P. SARS-CoV-2 Antibody Response After a Third Dose of the BNT162b2 Vaccine in Patients Receiving Maintenance Hemodialysis or Peritoneal Dialysis. Am J Kidney Dis. 2022 Feb;79(2):185-192.e1. doi: 10.1053/j.ajkd.2021.08.005. Epub 2021 Sep 8. PMID: 34508833; PMCID: PMC8425695.

Garcia P, Montez-Rath ME, Moore H, Flotte J, Fults C, Block MS, Han J, Dittrich M, Parsonnet J, Chertow GM, Block GA, Anand S. SARS-CoV-2 Vaccine Acceptability in Patients on Hemodialysis: A Nationwide Survey. J Am Soc Nephrol. 2021 Jul;32(7):1575-1581. doi: 10.1681/ASN.2021010104. Epub 2021 Apr 29. PMID: 33927004; PMCID: PMC8425649.

Mezue K, Edwards P, Nsofor I, Goha A, Anya I, Madu K, Baugh D, Nunura F, Gaulton G, Madu E. Sub-Saharan Africa Tackles COVID-19: Challenges and Opportunities. Ethn Dis. 2020 Sep 24;30(4):693-694. doi: 10.18865/ed.30.4.693. PMID: 32989369; PMCID: PMC7518544.

Blanchi S, Torreggiani M, Chatrenet A, Fois A, Mazé B, Njandjo L, Bianco G, Lepori N, Pili A, Michel PA, Sileno G, Arazzi M, Esposito V, Pani A, Versino E, Esposito C, Fessi H, Cabiddu G, Piccoli GB. COVID-19 Vaccine Hesitancy in Patients on Dialysis in Italy and France. Kidney Int Rep. 2021 Nov;6(11):2763-2774. doi: 10.1016/j.ekir.2021.08.030. Epub 2021 Sep 8. PMID: 34518807; PMCID: PMC8425747.

Andrian T, Koppe L, Novel E, Massat M, Barba C, Ioriatti D, Barnel C, Villar E, Luce M, Guerraoui A, Mezaache S, Kalbacher E, Tournebize C, Fouque D, Chalencon E. COVID-19 vaccine acceptance among haemodialysis patients: a French survey. Clin Kidney J. 2021 Apr 28;14(8):1985-1986. doi: 10.1093/ckj/sfab084. PMID: 34341684; PMCID: PMC8135361.

van Riel D, de Wit E. Next-generation vaccine platforms for COVID-19. Nat Mater. 2020 Aug;19(8):810-812. doi: 10.1038/s41563-020-0746-0. PMID: 32704139.

Reuters Staff [Internet]. False claim: A COVID-19 vaccine will genetically modify humans. Reuters. Disponible sur: https://uk.reuters.com/article/uk-factcheck-covid-19-vaccine-modify-idUSKBN22U2BZ.

Lurie P, Bishaw M, Chesney MA, Cooke M, Fernandes ME, Hearst N, Katongole-Mbidde E, Koetsawang S, Lindan CP, Mandel J, et al. Ethical, behavioral, and social aspects of HIV vaccine trials in developing countries. JAMA. 1994 Jan 26;271(4):295-301. PMID: 8295289.

Bhopal S, Nielsen M. Vaccine hesitancy in low- and middle-income countries: potential implications for the COVID-19 response. Arch Dis Child. 2021 Feb;106(2):113-114. doi: 10.1136/archdischild-2020-318988. Epub 2020 Sep 10. PMID: 32912868.

Ministère de la Santé et de la Prévention [Internet]. Vaccination contre le Covid en France : au 10 mai 2022, 41 479 876 doses de rappel ont été réalisées - [cité 4 sept 2022]. Disponible sur : https://sante.gouv.fr/archives/archives-presse/archives-communiques-de-presse/article/vaccination-contre-le-covid-en-france-au-10-mai-2022-41-479-876-doses-de-rappel

République du Sénégal [Internet]. Vaccination COVID 19 [cité 4 sept 2022]. Disponible sur: https://vaccincorona.sec.gouv.sn

Longlune N, Nogier MB, Miedougé M, Gabilan C, Cartou C, Seigneuric B, Del Bello A, Marion O, Faguer S, Izopet J, Kamar N. High immunogenicity of a messenger RNA-based vaccine against SARS-CoV-2 in chronic dialysis patients. Nephrol Dial Transplant. 2021 Aug 27;36(9):1704-1709. doi: 10.1093/ndt/gfab193. PMID: 34057463; PMCID: PMC8195197.

Rodríguez-Espinosa D, Broseta JJ, Maduell F, Bedini JL, Vera M. Humoral response of the mRNA-1273 SARS-CoV-2 vaccine in peritoneal dialysis patients. Kidney Int. 2021 Aug;100(2) 476-477. doi:10.1016/j.kint.2021.05.018. PMID: 34081947; PMCID: PMC8166036.

Panizo N, Albert E, Giménez-Civera E, Puchades MJ, D’Marco L, Gandía-Salmerón L, Giménez E, Torre I, Sancho A, Gavela E, Gonzalez-Rico M, Montomoli M, Perez-Baylach CM, Bonilla B, Solano C, Alvarado MF, Torregrosa I, Alcaraz MJ, Górriz JL, Navarro D. Dynamics of SARS-CoV-2-Spike-reactive antibody and T-cell responses in chronic kidney disease patients within 3 months after COVID-19 full vaccination. Clin Kidney J. 2022 Apr 9;15(8):1562-1573. doi: 10.1093/ckj/sfac093. PMID: 35880064; PMCID: PMC9047236.

Chen JJ, Lee TH, Tian YC, Lee CC, Fan PC, Chang CH. Immunogenicity Rates After SARS-CoV-2 Vaccination in People With End-stage Kidney Disease: A Systematic Review and Meta-analysis. JAMA Netw Open. 2021 Oct 1;4(10):e2131749. doi: 10.1001/jamanetworkopen.2021.31749. PMID: 34709385; PMCID: PMC8554642.

Grupper A, Sharon N, Finn T, Cohen R, Israel M, Agbaria A, Rechavi Y, Schwartz IF, Schwartz D, Lellouch Y, Shashar M. Humoral Response to the Pfizer BNT162b2 Vaccine in Patients Undergoing Maintenance Hemodialysis. Clin J Am Soc Nephrol. 2021 Jul;16(7):1037-1042. doi: 10.2215/CJN.03500321. Epub 2021 Apr 6. PMID: 33824157; PMCID: PMC8425628.

Seck SM, Mbow M, Kane Y, Cisse MM, Faye G, Kama A, Sarr M, Nitcheu P, Dahaba M, Diallo IM, Diawara MS, Latou LNM, Dia Y, Mboup S. Prevalence of SARS-CoV-2 antibodies in hemodialysis patients in Senegal: a multicenter cross-sectional study. BMC Nephrol. 2021 Nov 17;22(1):384. doi: 10.1186/s12882-021-02582-w. PMID: 34789170; PMCID: PMC8595275.

Zitt E, Davidovic T, Schimpf J, Abbassi-Nik A, Mutschlechner B, Ulmer H, Benda MA, Sprenger-Mähr H, Winder T, Lhotta K. The Safety and Immunogenicity of the mRNA-BNT162b2 SARS-CoV-2 Vaccine in Hemodialysis Patients. Front Immunol. 2021 Jun 16;12:704773. doi: 10.3389/fimmu.2021.704773. PMID: 34220867; PMCID: PMC8242233.

Cheng Y, Luo R, Wang K, Zhang M, Wang Z, Dong L, Li J, Yao Y, Ge S, Xu G. Kidney disease is associated with in-hospital death of patients with COVID-19. Kidney Int. 2020 May;97(5):829-838. doi: 10.1016/j.kint.2020.03.005. Epub 2020 Mar 20. PMID: 32247631; PMCID: PMC7110296.

Hsu CM, Weiner DE, Aweh G, Miskulin DC, Manley HJ, Stewart C, Ladik V, Hosford J, Lacson EC, Johnson DS, Lacson E Jr. COVID-19 Among US Dialysis Patients: Risk Factors and Outcomes From a National Dialysis Provider. Am J Kidney Dis. 2021 May;77(5):748-756.e1. doi: 10.1053/j.ajkd.2021.01.003. Epub 2021 Jan 17. PMID: 33465417; PMCID: PMC7816961.

Published

2023-07-18

How to Cite

1.
Ettoumi H, Mbengue M, Niang A. Acceptance of vaccination against COVID-19 among peritoneal dialysis patients in Senegal. Bull Dial Domic [Internet]. 2023 Jul. 18 [cited 2024 Dec. 22];6(2):59-68. Available from: https://bdd.rdplf.org/index.php/bdd/article/view/76733