Renal graft intolerance syndrome in peritoneal dialysis: a report on 3 cases
DOI:
https://doi.org/10.25796/bdd.v7i3.84583Keywords:
renal graft intolerance , peritoneal dialysis, transplantectomyAbstract
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Introduction:
Renal graft intolerance syndrome is a serious complication following return to dialysis, which may present as an atypical clinical picture. Transplantectomy is almost systematic.
We report the observation of three renal transplant patients currently on peritoneal dialysis who underwent renal graft nephrectomy with maintenance of peritoneal dialysis.
Observation:
These were 3 patients, 2 men and one woman with an average age of 40 years. The average duration of renal transplantation was 11 years. The cause of the return to dialysis was chronic graft dysfunction. After an average delay in PD of 22 months, 2 patients presented with asthenia and significant weight loss. One patient presented with acute fever and severe graft pain. This was associated with a chronic inflammatory syndrome. All patients underwent nephrectomy of the graft without interruption of the dialysis technique, with early resumption of exchanges. Pathological examination showed necrosis of the renal graft.
Conclusion:
Deterioration of general condition associated with an inflammatory syndrome and resistance to erythropoietin may reveal a renal graft intolerance syndrome. Transplantectomy is indicated to improve survival in these patients without compromising the peritoneal dialysis technique.
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Copyright (c) 2024 Sara El Maakoul, Yassir Tahri, Naima Ouzeddoun, Loubna Benamar
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