Patients’ outcome with polycystic kidney disease firstly treated with peritoneal dialysis. Experience of our home dialysis unit since 1997.

Authors

DOI:

https://doi.org/10.25796/bdd.v4i1.58843

Keywords:

peritoneal dialysis, peritonitis, renal transplantation, polycystic kidney disease

Abstract

We extracted data from the French Speaking Registry of Peritoneal Dialysis and retrospectively studied peritonitis and the outcome of 30 patients with polycystic kidney disease firstly treated with peritoneal dialysis within our dialysis unit since 1997.

There were 15 men and 15 women with a mean age of 54 years. Eighty-five per-cent of the patients had hepatic impairment. Ten patients did not suffer from comorbidities. Charlson comorbidity index was greater than or equal to 4 in five patients. Most of the patients was treated with automated peritoneal dialysis during the night. Only one patient was not autonomous with peritoneal dialysis. The whole medical monitoring lasted 836 months, representing an average of 28 months per patient. Eleven patients had a total of 24 peritonitis, 9 with gram negative bacillus. The incidence of peritonitis was one episode every 35 months-patient. Peritonitis was responsible for sudden admission in hemodialysis unit in two cases and death in one case. Fifteen patients (50%) benefited from renal transplantation. Only one patient had to undergo nephrectomy prior to renal transplantation. Seven patients were admitted to hemodialysis unit (the median duration time on peritoneal dialysis was 36 months). Four patients died. Four patients are currently treated with peritoneal dialysis.

In conclusion, this retrospective study points out that peritoneal dialysis, especially automated peritoneal dialysis, is a good option for patients with polycystic kidney disease necessitating dialysis.

References

Sigogne M, Kanagaratnam L, Dupont V, Couchoud C, Verger C, Maheut H et coll. Polykystose rénale autosomique dominante et dialyse péritonéale : études rétrospectives à partir de deux registres nationaux REIN et RDPLF. Néphrol et Ther. 2017; 13(5): 270.

Pirson Y. Extra-renal manifestations of autosomal dominant polycystic kidney disease. Adv Chronic Kidney Dis. 2010; 17(2): 173-180.

Haute Autorité de santé. Indications et non-indications de la dialyse péritonéale chronique chez l’adulte. Recommandations de bonne pratique. 16 octobre 2008.

Noel N, Rieu P. Pathophysiologie, épidémiologie, présentation clinique, diagnostic et options thérapeutiques dans la polykystose rénale autosomique dominante. Nephrol et Ther. 2015; 11(4): 213-225

Dupont V, Kanagaratnam L, Sigogne M, Bechade C, Lobbedez th, Portoles J et coll. Outcome of polycystic kidney disease patients on peritoneal dialysis: systematic review of literature and meta-analysis. PLos One 2018; 13(5): e0196769

Boonphiphop B, Thongprayoon C, Wijarnpreecha K, Medaura J, T Chebib FT, Cheungpasitporn W. Outcomes of patients with autosomal-dominant polycystic kidney disease on peritoneal dialysis: a meta-analysis. Nephrology 2019; 24: 638-646

Sigogne M, Kanagaratnam L, Mora C, Pierre M, Petrache A, Marcus C et coll. Etude des facteurs associés à la pression intra-péritonéale chez les patients atteints de polykystose hépatorénale autosomique dominante et traités par dialyse péritonéale. Nephrol et Ther. 2019; 15(5): 266

Hadimeri H, Johansson AC, Haraldsson B, Nyberg G. CAPD in patients with autosomal-dominant polycystic kidney disease. Périt Dial Int. 1998; 18: 429-432

Ryckelynck JP, Abbadie O, Castrale C, Lavainne F, Fakhouri F, Lobbedez T. Pourquoi et comment promouvoir la Dialyse péritonéale ? Presse Med. 2011; 40(11): 1053-1058

Lobbedez Th, Touam M, Evans D, Ryckelynck J-Ph, Knebelman B, Verger Ch. Peritoneal dialysis in polycystic Kidney disease patients. Report from the French peritoneal dialysis registry (RDPLF). Nephrol Dial transplant 2011; 7: 2332 – 2339.

Recommandations ISPD concernant les infections en dialyse péritonéale (traduction Française) : mise à jour 2010. Perit Dial Int 2010; 30: 393-423

Courivaud C, Roubiou C, Delabrousse E, Bresson-Vautrin C, Chalopin JM, Ducloux D. Polycystic kidney size and outcomes on peritoneal dialysis: comparison with haemodialysis. Clin Kidney J. 2014; 7(2): 138-143

Zhou C, Gu Y, Mei C, Dai B, Wang Y, Xue C. Dialysis modality and mortality in polycystic kidney disease. Hemodial Int. 2018; 22(4): 515-523

Xingxing F, Meizi K, Dongmei C, Lianglan S. Comparison of mortality between peritoneal dialysis and hemodialysis in polycystic kidney disease. Renal Failure 2019; 41(1): 14-15

Published

2021-04-07

How to Cite

1.
Poux jean- michel, Cardozo C, Maurice L, Jolivot A, Fauvel J-P. Patients’ outcome with polycystic kidney disease firstly treated with peritoneal dialysis. Experience of our home dialysis unit since 1997. Bull Dial Domic [Internet]. 2021 Apr. 7 [cited 2024 Nov. 22];4(1):11-9. Available from: https://bdd.rdplf.org/index.php/bdd/article/view/58843